Building a mechanism of science and technology innovation activities in a region is required, which is to make use of the characteristics and strengths of regions and can be deployed autonomously. Therefore, universities are expected to work with such local companies as a member of the local community, and to contribute to the construction of a regional innovation system. Then, in order to clarify the achievements and issues of the industry academic collaboration in region, the National Institute of Science and Technology Policy(NISTEP) conducted research on industry-academia collaboration to target the manufacturing industry in Kagoshima Prefecture as a case study in fiscal year 2011 (Sotohebo-Nakatake 2012). In 2012 we conducted a questionnaire survey by mail to target the 700 manufacturing companies to put headquarters, factories, and offices in Gunma prefecture, and the survey was obtained valid responses of 190 companies (27.1% response rate).Of the respondents of this survey, there is over one third of (34.7%) companies had experience of cooperation with academia. Many companies initiated the industry-academia collaboration from the 1990s. There are 53 companies which had cooperation with Gunma University. This is 27.9% of the total answer. In Gunma University, research and development has been more active. In the evaluation of a result of industry-academia collaboration, improvement of technical level is high. In the prefecture, there were some companies that promote research and development without industry-academia collaboration. In order to activate the industry-academia collaboration in the region, it is necessary that we can promote to these R&D-oriented companies in steadily announce on the benefits of collaboration with university and in building relationship between industry and academia.
